Ethno Botanical Potential for Medicinal Ferula assa-foetida as a main Medical Plant in East of Iran

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Double edged effect of gum-resin of ferula assa-foetida on lifespan of neurons

OBJECTIVE(S) Based on knowledge from traditional herbal medicine, Ferula assa-foetida (asafoetida) has several therapeutic applications but there is less knowledge about its effect on neurons. MATERIALS AND METHODS In order to evaluate neuronal differentiation, neuronal like cells were stained against neuronal specific markers β-Tubulin III and MAP2. After establishment of neuronal differenti...

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Acute and subchronic toxicity assessment model of Ferula assa-foetida gum in rodents.

AIM The present study was performed to investigate acute and subchronic oral toxicity of Ferula assa-foetida gum (28 days) in Sprague Dawley rats. MATERIALS AND METHODS Acute oral administration of F. assa-foetida was done as a single bolus dose up to 5 g/kg in mice and subchronic toxicity study for 28 days was done by oral administration at doses of 0 (control) and 250 mg/kg in Sprague Dawle...

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Essential oil analysis and antibacterial activity of Ferula assa-foetida L. aerial parts from Neishabour mountains

Background and objectives: Ferula assa-foetida (asafoetida) is a native Iranian species which grows in different regions and climates in Iran. The plant is well known in Iranian Traditional Medicine as well as folk medicine for treatment of diseases. Several studies have been carried out on the essential oil of this species collected from different areas of Iran. This study is the first report ...

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Effects of Ferula assa-foetida extract on spermatogenesis of rats

Background and objectives: Ferula assa-foetida is an herbaceous perennial plant which belongs to Apiaceae family. It is native to the east and central parts of Iran. This old traditional medicine has been used as antispasmodic, carminative, expectorant, laxative, sedative, stimulant, emmenagogue and vermifuge. In addition to the several therapeutic effects of the plant...

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Antileishmanial activity of Ferula assa-foetida oleo gum resin against Leishmania major: An in vitro study

BACKGROUND In Ayurveda, asafetida is introduced as a valuable remedy for flatulence, hysteria, nervous disorders, whooping cough, pneumonia and bronchitis in children and also considered as an aphrodisiac agent. Presently, Leishmaniasis is common in most countries of the world and is a serious health problem in the world. Some plant medicines and natural products have a new candidate for treatm...

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ژورنال

عنوان ژورنال: Journal of AgriSearch

سال: 2016

ISSN: 2348-8867,2348-8808

DOI: 10.21921/jas.v3i4.6708